Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. 

Why Join Our Medical Affairs Team? 

• Innovative Environment: Join the global leader in precision cancer immunotherapy and help drive the launch of our first PRAME-targeted therapy, anzu-cel. Your work will directly support a team at the forefront of scientific and clinical breakthroughs. 

• Collaborative Culture: You will be part of a diverse and agile team that values your initiative, discretion, and ability to enable team productivity and growth. 

• Global Impact: Support a mission that extends far beyond the office. At Immatics, your expertise helps accelerate therapies that target more than 50 cancers, improving outcomes for patients worldwide. 

Position Overview: 

The Executive Director, Medical Affairs (East), is a seasoned medical affairs leader with 

oncology/hematology expertise, strong business acumen, and an established history of shaping medical strategy and driving medical launch readiness and execution in the US market. 

The ideal candidate will have robust experience working in close partnership within a highly functioning, matrix team. He/she will be an integral part of the Medical Affairs leadership team and will partner closely with the Executive Director, Medical Affairs (West) to ensure nationwide alignment, operational excellence, and consistent field impact. This individual will directly manage and develop the Eastern US MSL field team. Areas of focus include developing field medical strategy guiding the field medical team's externally facing activities, coordinating/executing engagements with external stakeholders, supporting publications strategy, and representing the field medical team (East), both internally and externally, to support ongoing pipeline development. 

The Executive Director, Medical Affairs (East) will also provide leadership and oversight for Patient Advocacy strategy and partnerships, ensuring strong collaboration with internal and external partners to advance patient-focused initiatives. 

FLSA Classification: Salary, Exempt 
Schedule: 8:00 AM – 5:00 PM; Monday to Friday; Remote 
Reports to: Vice President, Medical Affairs  
Location: Fully Remote  

What You’ll Do: 

Team Leadership & Development 

• Establish and lead the Eastern region of MSLs, including recruitment, onboarding, and performance development.  

• Manage a geographically dispersed team covering the Eastern half of the US, ensuring consistent, high-quality scientific engagement and field execution. 

• Build a culture of scientific excellence, accountability, and collaboration aligned with Immatics’ mission. 

• Ensure the team operates in compliance with internal SOPs, company standards, and regulatory requirements. 

• Provide coaching, mentorship, and performance management to ensure MSL effectiveness and growth. 

Strategic Field Execution 

• Translate Medical Affairs objectives into clear field medical strategies that enhance scientific exchange, trial support, and data generation activities. 

• Guide MSL engagement with investigators, opinion leaders, and treatment centers to support trial execution, insights capture, and regional education. 

• Drive regional readiness and scientific fluency for launch and pipeline programs, ensuring alignment with overall US strategy. 

• Oversee field medical coverage for national and regional congresses ensuring seamless pre-, on-site, and post-congress execution. 

• Ensure external scientific interactions are conducted in a compliant and balanced manner. 

Pre-Launch & Launch Readiness 

• Drive regional execution of launch readiness for TCR T-cell therapy programs, including scientific education, stakeholder mapping, and insights integration. 

• Partner with cross-functional teams to ensure consistent launch messaging and field preparedness. 

• Contributes to early engagement and launch planning for future pipeline programs across solid tumors. 

Patient Advocacy 

• Provide strategic oversight for Patient Advocacy, including trial awareness and education, sponsorship support, professional society collaboration, and executive-level advocacy engagement that strengthen Immatics’ partnerships with the patient community. 

Training, Tools & Readiness 

• Partner with the Medical Training & Content Senior Director to ensure MSLs are equipped with accurate, compliant, and effective field materials.  

• Identify regional training needs, refine resources, and continuously strengthen field capabilities.  

Cross-Regional & Functional Collaboration 

• Collaborate closely with the Executive Director, Medical Affairs (West) to ensure national alignment of field medical strategy, processes, and communication. 

• Collaborate with other internal partners to align external engagement strategies and optimize impact. 

Insights & Analytics 

• Establish processes for capturing and reporting actionable insights from KOLs, investigators, and treatment centers. 

• Monitor team performance using KPIs, dashboards, and qualitative impact measures to assess field effectiveness. 

• Translate regional insights into strategic recommendations that inform medical planning and decision-making.  

Required Experience and Education: 

• Advanced degree (i.e. MD, PharmD, PhD, APN) in a life-sciences discipline 

• 15+ years progressive experience across clinical and the biopharmaceutical industry (including 7+ years of medical affairs experience) 

• Prior experience building, leading and coaching an MSL team is required 

• Oncology/hematology experience required 

• Cell therapy experience preferred

• Launch experience within oncology/hematology cell therapy in the US market strongly preferred 

• Experience working and influencing in a matrix environment with other functional groups (e.g. Regulatory, Clinical Development, Clinical Operations, Commercial) 

Preferred Experience and Education:  

• Demonstrated ability to inspire, develop, and retain top MSL talent. 

• Skilled in fostering cross-functional collaboration and trusted partnerships with KOLs, investigators, advocacy partners, and stakeholders. 

• Exceptional communication skills with the ability to synthesize and present complex scientific information clearly. 

• Proven success elevating field medical teams as strategic partners within Medical Affairs and the broader organization. 

Competencies  

• Initiative 

• Problem Solving 

• Critical Thinking 

• Interpersonal Communication 

• Customer Service 

• Attention to Detail 

Work Environment:  

This is a sedentary position (at least 50% of time) in a typical office environment. There may be frequent interruptions with moderate noise levels and frequent use of printers, copiers, scanners, computers and other office equipment. Ability to sit, talk, walk, hear and communicate verbally and in writing is required. Occasional lifting of objects up to 25 lbs is expected.    

Physical demands: 

• Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly. 

• Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds. 

• Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.  

• Lifting - raising or lowering an object (up to 25 lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or arms but may occur on the shoulder. 

• Near Visual Acuity – clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).  

• Pushing - Exerting force upon an object so that the object moves away from the object. 

• Pulling - Exerting force upon an object so that the object moves toward the force.  

• Sitting – remaining in a sitting position for at least 50% of the time. 

• Standing/Walking - remain on one's feet in an upright position at a workstation.  

• Stooping – occasional bending the body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles. 

Work authorization/security clearance requirements:  

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment   

Affirmative Action/EEO statement:   

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.  

What do we offer?  

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics 

Comprehensive Benefits:  

• Competitive rates for Health, Dental, and Vision Insurance 

• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment. 

• Sick Time Off – 56 hours  

• 12 Paid Holidays  

• 100% Employer-Paid Life Insurance up to at 1x annual salary 

• 100% Employer Paid Short- and Long-Term Disability Coverage  

• 401(k) with Immediate Eligibility  & company match… 

• You are eligible for 401(k) plan participation as of your first paycheck. 

• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment. 

• Partially paid Parental Leave for eligible employees. (3 weeks) 

• Additional voluntary employee paid coverages including  Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.  

Professional Growth:  

• Opportunities to work with leading experts in the field of T-cell immunotherapy.  

• Company provided learning and development opportunities 

• Fast paced, high demand collaborative and dynamic environment.