Compensation:

$70,000 - $85,000 per year. You are eligible for a Short-Term Incentive Plan with the target at 5% of your annual earnings; terms and conditions apply.

Research Associate II – Onsite in Aliso Viejo, CA

The Research Associate II is responsible for supporting the design, development and execution of novel assays based on Next-Generation Sequencing and Long Read Sequencing. This role supports Ambry’s translational research initiatives, including internal and external collaborations, working under minimal supervision. This position will work as part of a multi-disciplinary team including R&D scientists, bioinformatics scientists, project managers and clinical laboratory personnel. 

 Essential Functions

• Perform DNA/RNA isolation from biospecimens such as blood, saliva, and buccal swabs
• Library preparation for long/short read sequencing. Monitoring of sequencing metrics
• Tracking project progress and maintenance of up-to-date electronic laboratory notebook 
• Conduct data analyses and present during internal and external meetings 
• Drafting work instructions, standard operating procedures and other supporting documentation
• Contribute to the design and development of novel assays for use in translational research projects and support their transition to the clinical setting
• Other duties as assigned  

Qualifications

• BS or MS degree in a life sciences field: Biology, Molecular Biology, Biochemistry, or related field
• Strong understanding of molecular biology and genetics 
• Experience with DNA/RNA extraction from biospecimen such as whole blood, saliva and buccal swabs
• Experience with library preparation for short or long read sequencing and subsequent analysis and interpretation of sequencing metrics 
• Experience with molecular biology techniques such as PCR and gel electrophoresis
• Good command of Word, Excel and PowerPoint, or equivalent office programs

Preferred

• BS with 3+ years or MS with 1+ years of laboratory research experience in an academic or industrial setting
• Strong understanding and previous experience working on human genetics 
• Proficient in the following molecular biology techniques: library preparation for short or long read sequencing, DNA/RNA extraction from biospecimens (blood/saliva/buccal), PCRs and analysis of electrophoretic traces
• Excellent verbal and written communication skills and ability to communicate and work effectively as part of a multidisciplinary team
• Ability to present organized summaries to internal or external stakeholders. 
• Excellent organizational and record keeping skills
• Strong willingness to learn new laboratory techniques and procedures, as well as expand your knowledge about genetic variation and its connection to genetic diseases
• Previous experience or interest in learning more about data interpretation
• Good command of sequencing metrics interpretation  
• Previous hands-on experience with long-read sequencing will be positively valued

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