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Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America

Job Description:

We are searching for the best talent for our Associate Scientist II, In Vitro Display, located in Cambridge, MA.

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Purpose:

We are seeking an outstanding Associate Scientist II for our in vitro discovery and protein engineering group, who can support the development, implementation, and utilization of phage and yeast display libraries for antibody discovery, or other emerging molecular optimization techniques to support the development of biologics (multispecific antibodies, CAR-T, ADCs, etc.) in various disease areas. The position offers an exciting opportunity to engage in the discovery and molecular engineering of biotherapeutics while also developing new processes and technologies for biologics discovery. The position's responsibilities also include portfolio project leadership and interaction with world-class scientists in different therapeutic areas, including oncology, immunology, metabolic diseases, neurology, and infectious diseases. This position is laboratory-based, requiring adherence to safety protocols and the ability to work with biological samples and chemicals.

You will be responsible for:

• Performing and optimizing in vitro display techniques such as phage display and yeast display for molecule discovery and selection.
• Conducting experiments involving DNA/RNA library construction, DNA purification, protein expression, purification, and characterization.
• Executing assays to evaluate the binding, off-rate, and functionality of selected candidates (flow cytometry, ELISA, Octet, etc.).
• Analyzing, interpreting, and documenting experimental data while maintaining accurate and detailed records.
• Collaborating with cross-functional teams to support project objectives and timelines.
• Contributing to troubleshooting, protocol development, and the continuous improvement of laboratory workflows.
• Preparing technical reports, presentations, and summaries for internal discussions and external collaborations.

Qualifications:

• Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Biotechnology, or a related field.
• Hands-on experience with molecular biology techniques, such as PCR, cloning, and transformations, etc.
• Familiarity with in vitro display technologies (e.g., phage display, yeast display) is highly desirable.
• Proficiency in assay development, including ELISA and other binding/activity assays, is a plus.
• Strong analytical and problem-solving skills with the ability to manage multiple projects simultaneously.
• Excellent written and verbal communication skills.
• Demonstrated ability to work both independently and collaboratively in a dynamic research environment.

Preferred Qualifications:

• Experience with automation platforms or high-throughput screening systems.
• Knowledge of bioinformatics tools for sequence analysis and library design.
• Prior experience in therapeutic discovery or biotechnology industries.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

#LI-Onsite

Required Skills:

 

 

Preferred Skills:

 

 

The anticipated base pay range for this position is :

$76,000.00 - $121,900.00

Additional Description for Pay Transparency:

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:

Vacation –120 hours per calendar year

Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year

Holiday pay, including Floating Holidays –13 days per calendar year

Work, Personal and Family Time - up to 40 hours per calendar year

Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child

Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year

Caregiver Leave – 80 hours in a 52-week rolling period10 days

Volunteer Leave – 32 hours per calendar year

Military Spouse Time-Off – 80 hours per calendar year

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits