The Mo lab seeks to understand the mechanisms of neurodevelopmental disorders using molecular biology, genomic, biochemical, and computational approaches. We are broadly interested in two areas: 1) the impacts of somatic mutations in brain development and disease; and 2) the mechanisms of specific genetic causes of autism and intellectual disability. Ongoing projects include using induced pluripotent stem cells and neural progenitor cells to model somatic mosaicism, characterizing the distribution of somatic mosaicism in neurotypical and autism brains, and using single cell multiomic techniques to study specific subtypes of autism. We use a variety of techniques and materials such as next generation sequencing, cell culture models, postmortem human brain tissue, and computational tools.

 

 

Performs research experiments in accordance with provisions of the approved protocol, maintains records, prepares reports and publications, and assists in analyzing data.

 

 

Essential Functions:

• Performs semi-independent research experiments reliably and reproducibly in accordance with protocols approved by the principal investigator.
• Collects and curates experimental data, maintains accurate daily logs of experiments including methods and results, and draws preliminary conclusions.
• Assists the principal investigators in the preparation of scientific publications, grant proposals, and presentations.
• Maintains inventory of equipment and supplies and ensures that research equipment is in good working order.
• Follows all appropriate lab safety protocols and other regulatory requirements.

Education Requirement:

Bachelor’s Degree in relevant field, required.

Experience:

Research experience, preferred.

Physical Requirements:

OCCASIONALLY: Bend/twist, Biohazard waste, Chemicals/Medications, Climb stairs/ladder, Cold Temperatures, Fume /Gases /Vapors, Hot Temperatures

FREQUENTLY: Lifting / Carrying: 0-10 lbs, Lifting / Carrying: 11-20 lbs, Pushing / Pulling: 0-25 lbs, Pushing / Pulling: 26-40 lbs, Standing, Walking

CONTINUOUSLY: Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Flexing/extending of neck, Hand use: grasping, gripping, turning, Hearing acuity, Interpreting Data, Peripheral vision, Problem solving, Reaching above shoulder, Repetitive hand/arm use, Seeing – Far/near, Sitting, Squat/kneel

 

 

"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"