Metabolite Isolation Intern

  • Neurocrine Continental Inc.
  • US CA San Diego
  • 4mo ago
  • Full-Time
  • On-site

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedInX and Facebook. (*in collaboration with AbbVie)

About the Role:

Neurocrine Biosciences, Inc. (NASDAQ: NBIX) is offering the opportunity to gain experience in isolating drug metabolites by UPLC/MS-Fraction collection in the world of biotechnology. Our intern program offers exposure to biosynthesis of metabolites using sub-cellular liver fractions, semi-preparative chromatography, HRMS (high resolution mass spectrometry), and possibly NMR (Nuclear Magnetic Spectroscopy). The Biotransformation team has a strong reputation in the industry for metabolite identification.

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Your Contributions (include, but are not limited to):

  • Working with sub-cellular fractions (liver microsomes, and S9) to generate metabolites.
  • Working with semi-preparative UPLC-Fraction collector to isolate metabolites from parent compound.
  • Analysis of individual fractions by UPLC/HRMS to confirm fraction isolation of metabolite.
  • Interacting with drug metabolism areas within the company
  • Collaborating with a mentor team of cross-functional team members as well as the other interns in the class
  • Completing a special project and presenting the recommendations to senior management upon completion

Requirements:

  • Pursuing an undergraduate degree with an interest in biotechnology
  • Specific degree or field required: The ideal candidate would be in their 3rd or 4th year pursuing an undergraduate degree in chemistry, biology, biotechnology, or relevant pharmaceutical sciences.
  • Prior experience in the pharmaceutical or biotechnology industry would be an asset but is not required
  • Familiarity with biopharmaceutical technologies, physical and life sciences, product development, and regulatory approval processes is desirable
  • Good verbal and written communication skills
  • Ability to think creatively and be a team player
  • Offer flexibility with a willingness to work on multiple projects simultaneously
  • Bring to the Company a skill set complementary to its technology and development therapeutics
  • Interest in attending various program events, including social gatherings, career development workshops, and more
  • Ability to commit to a 10-week, full-time summer program
  • Lab Work Requirements: Part-timeA significant amount of time will be spent lab based but remote access of instrumentation, data analysis, and presentation of results from office space are also a part of the role.

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.