Scientist, Translational Biology

  • Neurocrine Continental Inc.
  • US CA San Diego
  • 1w ago
  • Full-Time
  • On-site

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedInX and Facebook. (*in collaboration with AbbVie)

About the Role:

Performs assigned experiments to support scientific activities in mice and rats with compound formulation and dosing using various routes of administration (particularly ICV), behavioral testing (motor, cognitive, etc), data handling, and tissue collection. Directly involved in assay development for in vivo examination of novel drug targets and screening of potential therapeutic compounds, study design, execution of procedures and data analysis in a team setting.

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Your Contributions (include, but are not limited to):

  • Performs assigned experiments to support scientific activities and project goals involving transgenic mouse colony maintenance and breeding

  • May design less complex experiments

  • Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions to problems

  • Works with stereotaxic surgical techniques, microdialysis and/or EEG

  • Oversees AAV dosing via multiple routes of administration

  • Responsible for behavioral assay development, validation and screening

  • Completes data analysis and reporting. Maintains and updates SOP’s and writes data summaries for experiments conducted

  • Handles and doses animals in a laboratory setting

  • Reviews, comprehends and complies with all SOP’s, IACUC procedures, and safety and quality assurance standards at all times

  • Provides training and/or supervision to junior staff, as needed

  • Other duties as assigned

Requirements:

  • BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and 2+ years of experience in the handling and dosing of rodents in a laboratory setting OR

  • MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred OR

  • PhD degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred

  • Additional stereotaxic surgery, microdialysis and/or EEG experience strongly preferred

  • Working knowledge of stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding

  • Previous experience with stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding preferred

  • Extensive hands-on knowledge of behavioral testing in a variety of assays

  • Occasional weekend work required

  • Recognizes fundamental anomalies in data points and identifies issues in experiments/processes

  • Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals

  • Strong knowledge of one scientific discipline

  • Good knowledge of scientific principles, methods and techniques

  • Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools

  • Strong computer skills

  • Good communications, problem-solving, analytical thinking skills

  • Ability to meet deadlines

  • Good project management skills

  • High level of organization and attention to detail

  • Willingness and ability to work both independently and as part of a team

  • Must have working knowledge of Microsoft Office, Word, and Excel

  • Advanced multitasking, trouble shooting and deductive reasoning skills required

#LI-LS1

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $89,800.00-$123,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.