Post-Doc Fellow Lab for Regenerative Cell Therapy
- 2410 Brigham and Women's Physicians Organization, Inc.
- Boston-MA
- 4mo ago
- Full-Time
- On-site
...
Site: Massachusetts General Physicians Organization, Inc.
In 2018, the Department of Neurosurgery, MGH and the Laboratory of Molecular Neurobiology at McLean Hospital, both affiliated with Harvard Medical School, jointly completed the world's first FDA-approved autologous hiPSC-differentiated dopamine precursor cell implantation for the treatment of Parkinson's disease (N Engl J Med. 2020; 382:20 1926-1932). In 2023, the George A. “Doc” Lopez Laboratory for Regenerative Cell Therapy was established in the Department of Neurosurgery at MGH in honor of this achievement, to support ongoing and future clinical trials of cell therapy for Parkinson's disease (NCT06687837), and to develop and implement next generation cell production methods and novel cell therapies. The laboratory also focuses on disease mechanisms as a basis for developing new therapies, with an emphasis on transformative translational applications to Parkinson's disease and related neurodegenerative diseases. The laboratory includes both a GMP facility to produce clinical-grade cells for human clinical trials, and a neurobiology laboratory for preclinical research. The Laboratory is jointly directed by Scientific Director Bin Song, MD, PhD and Clinical Director Jeffrey Schweitzer, MD, PhD, both Assistant Professors of Neurosurgery of Harvard Medical School, in the Departments of Neurosurgery at Mass General Brigham.
The Laboratory website is: https://www.massgeneral.org/neurosurgery/research-and-clinical-trials/lopez-laboratoryOnsite55 Fruit StreetMassachusetts General Physicians Organization, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
"The George A. “Doc” Lopez, MD, Laboratory for Regenerative Cell Therapy" (Lopez Lab) in the Department of Neurosurgery at Massachusetts General Hospital (MGH), a teaching affiliate of Harvard Medical School in Boston, Massachusetts, USA seeks motivated candidates to join our team at the postdoctoral research level.In 2018, the Department of Neurosurgery, MGH and the Laboratory of Molecular Neurobiology at McLean Hospital, both affiliated with Harvard Medical School, jointly completed the world's first FDA-approved autologous hiPSC-differentiated dopamine precursor cell implantation for the treatment of Parkinson's disease (N Engl J Med. 2020; 382:20 1926-1932). In 2023, the George A. “Doc” Lopez Laboratory for Regenerative Cell Therapy was established in the Department of Neurosurgery at MGH in honor of this achievement, to support ongoing and future clinical trials of cell therapy for Parkinson's disease (NCT06687837), and to develop and implement next generation cell production methods and novel cell therapies. The laboratory also focuses on disease mechanisms as a basis for developing new therapies, with an emphasis on transformative translational applications to Parkinson's disease and related neurodegenerative diseases. The laboratory includes both a GMP facility to produce clinical-grade cells for human clinical trials, and a neurobiology laboratory for preclinical research. The Laboratory is jointly directed by Scientific Director Bin Song, MD, PhD and Clinical Director Jeffrey Schweitzer, MD, PhD, both Assistant Professors of Neurosurgery of Harvard Medical School, in the Departments of Neurosurgery at Mass General Brigham.
The Laboratory website is: https://www.massgeneral.org/neurosurgery/research-and-clinical-trials/lopez-laboratory
Qualifications
The Laboratory is now recruiting for 1 postdoctoral fellow. Candidate qualifications should include a PhD or MD degree in a relevant field such as neuroscience, stem cell biology, gene editing, immunology, cellular neurophysiology etc., with evidence of scholarly achievement including relevant publications. Familiarity with clinical neuroscience or other biological or medical backgrounds is preferred.
Highly valued qualifications include:
1. Experience in stem cell culture and neuron differentiation
2. Experience in neurodegenerative disease animal models, neural circuit analysis, optogenetics, chemical genetics, or electrophysiology
3. Experience in gene editing, molecular biology
4. Experience in immunology
5. Teamwork spirit and communication skills
Additional Job Details (if applicable)
Application Process:
Please send CV to Dr. Bin Song: bsong@mgh.harvard.edu or Dr. Jeffrey Schweitzer jschweitzer1@mgh.harvard.edu
Massachusetts General Hospital is an affirmative action/equal opportunity employer and encourages applications from women and underrepresented minorities.
Remote Type
Work Location
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.